食品科学2011，Vol.32Issue(17)：225-229,5.
鸡蛋卵转铁蛋白过敏原B细胞线性表位的预测研究
Prediction of B-cell Linear Epitopes in Egg Allergen Ovotransferrin
摘要
Abstract
In order to predict B-cell linear epitopes of egg allergen ovotransferrin（OVT）,the antigen index,hydrophilicity,and surface accessibility and flexibility of egg OVT were predicted using Jameson-Wolf,Kyte-Doolittle,Emini and Karplus-Schulz methods,respectively.The secondary structure of OVT was predicted by Chou-Fasman and Deleage-Roux methods based on the amino acid sequence of egg OVT derived from Genbank.Based on the above comprehensive analysis,7 possible B-cell linear epitope candidates in egg OVT were predicted to locate in the regions of 174-181,215-222,231-240,288-294,332-344,415-429 and 547-555.These results are useful for fine mapping of B-cell epitopes in egg OVT.关键词
卵转铁蛋白/B细胞线性表位/鸡蛋过敏/预测Key words
ovotransferrin/B-cell linear epitope/egg allergy/prediction分类
生物科学引用本文复制引用
佟平,高金燕,陈红兵,李欣,简姗,张银..鸡蛋卵转铁蛋白过敏原B细胞线性表位的预测研究[J].食品科学,2011,32(17):225-229,5.基金项目
国家自然科学基金项目 （）
教育部新世纪优秀人才支持计划项目 （）
南昌大学食品科学与技术国家重点实验室目标导向项目 （）
