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植物甾醇酯对高脂血症小鼠的降血脂作用研究

王玉 刘滨城 任运宏 胡立志 于殿宇

食品科学2011,Vol.32Issue(17):326-329,4.
食品科学2011,Vol.32Issue(17):326-329,4.

植物甾醇酯对高脂血症小鼠的降血脂作用研究

Lipid-lowering Effect of Phytosterol Ester in Hyperlipidemic Rats

王玉 1刘滨城 1任运宏 1胡立志 1于殿宇1

作者信息

  • 1. 东北农业大学食品学院,黑龙江哈尔滨150030
  • 折叠

摘要

Abstract

In this study,the effect of phytosterol ester at different dosages on serum lipid level of hyperlipidemic mice was investigated.A hyperlipidemic mouse model was established by feeding high fat diet,and then the mice were administered with phytosterol ester at the dosages of 50,75,100,125 mg/(kg·d) and 150 mg/(kg·d),respectively.The results showed that phytosterol ester could significantly reduce total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C) and arteriosclerosis index(AI) through increasing HDL-C/LDL-C and HDL-C/TC index when compared with hyperlipidemic group.However,no significant effect of phytosterol ester on triglyceride(TG) level was observed.In addition,phytosterol ester could regulate serum lipid level at the dose of 75 mg/(kg·d) for phytosterol ester(P〈0.05).

关键词

植物甾醇酯/小鼠/高脂血症/降血脂

Key words

phytosterol ester/mice/hyperlipidemia/hypolipidemia

分类

农业科技

引用本文复制引用

王玉,刘滨城,任运宏,胡立志,于殿宇..植物甾醇酯对高脂血症小鼠的降血脂作用研究[J].食品科学,2011,32(17):326-329,4.

基金项目

黑龙江省教育厅科技攻关项目 ()

食品科学

OA北大核心CSCDCSTPCD

1002-6630

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