食品科学2011,Vol.32Issue(17):326-329,4.
植物甾醇酯对高脂血症小鼠的降血脂作用研究
Lipid-lowering Effect of Phytosterol Ester in Hyperlipidemic Rats
摘要
Abstract
In this study,the effect of phytosterol ester at different dosages on serum lipid level of hyperlipidemic mice was investigated.A hyperlipidemic mouse model was established by feeding high fat diet,and then the mice were administered with phytosterol ester at the dosages of 50,75,100,125 mg/(kg·d) and 150 mg/(kg·d),respectively.The results showed that phytosterol ester could significantly reduce total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C) and arteriosclerosis index(AI) through increasing HDL-C/LDL-C and HDL-C/TC index when compared with hyperlipidemic group.However,no significant effect of phytosterol ester on triglyceride(TG) level was observed.In addition,phytosterol ester could regulate serum lipid level at the dose of 75 mg/(kg·d) for phytosterol ester(P〈0.05).关键词
植物甾醇酯/小鼠/高脂血症/降血脂Key words
phytosterol ester/mice/hyperlipidemia/hypolipidemia分类
农业科技引用本文复制引用
王玉,刘滨城,任运宏,胡立志,于殿宇..植物甾醇酯对高脂血症小鼠的降血脂作用研究[J].食品科学,2011,32(17):326-329,4.基金项目
黑龙江省教育厅科技攻关项目 ()