食品科学2011，Vol.32Issue(17)：339-343,5.
中链甘油三酯微胶囊的体外释放及对小鼠脂质代谢的影响
Release Characteristics in vitro of Medium-chain Triglyceride Microcapsules and Its Effect on Lipid Metabolism in Mice
摘要
Abstract
Medium-chain triglycerides（MCTs） were microencapsulated by spray-drying method with the purpose of solidification,which makes it convenient to add and store MCTs.In the present study,artificial gastric fluid was used to preliminarily investigate release characteristics in vitro of MCT microcapsules.Net basic synthetic diet,long-chain triglyceride（LCT） microcapsule-supplemented diet（the energy of LCTs accounting for about 30% of total energy） and MCT microcapsule-supplemented diet（（the energy of MCTs accounting for about 30% of total energy） were separately used to feed mice for 5 consecutive weeks.The changes in health status,body weight,the levels of serum triglyceride（TG）,total cholesterol（TC）,high-density lipoprotein cholesterol（HDL-C）,low-density lipoprotein cholesterol（LDL-C） and food intake of mice were observed during the period to understand the effect of MCT microcapsules on lipid metabolism in mice.The results showed that the release of MCT microcapsules in artificial gastric fluid could last 6 h so that abdominal pain and diarrhea caused by excessive intake of MCTs at one time could be relieved.The contents of TC and LDL-C in mice were reduced by supplementing MCT microcapsules in basic synthetic diet and meanwhile,the functions to prevent obesity,reduce body weight gain and fat accumulation and attenuate fat deposition in the liver.Furthermore,the mechanisms of inhibition of body weight gain were independent on reduced energy intake.关键词
中链甘油三酯/微胶囊/体外释放/脂质代谢Key words
medium-chain triglycerides/microcapsule/release in vitro/lipid metabolism分类
轻工纺织引用本文复制引用
王风新,邓波,熊华,窦晓凤..中链甘油三酯微胶囊的体外释放及对小鼠脂质代谢的影响[J].食品科学,2011,32(17):339-343,5.基金项目
南昌大学食品科学与技术国家重点实验室目标导向项目 （）
