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桑白皮总黄酮的抗氧化与镇痛活性研究

崔珏 李超 姜中生

食品科学2011,Vol.32Issue(23):281-284,4.
食品科学2011,Vol.32Issue(23):281-284,4.

桑白皮总黄酮的抗氧化与镇痛活性研究

Antioxidant and Analgesia Activities of Total Flavonoids from the Root Bark of Morus alba

崔珏 1李超 1姜中生1

作者信息

  • 1. 徐州工程学院食品生物工程学院,江苏徐州221008
  • 折叠

摘要

Abstract

Objective: To evaluate the antioxidant and analgesic activities of total flavonoids from the root bark of Morus alba.Methods: The antioxidant activity was evaluated by DPPH and hydroxyl free radical scavenging assays using VC as reference standard,and the analgesia activity by acetic acid-induced writhing response,formaldehyde-induced feet-licking response,and heat-induced pain threshold in mice.Results: The total flavonoids had obvious scavenging activity in vitro against DPPH and hydroxyl free radicals.These compounds resulted in a notable decrease in acetic acid-induced writhing number and feet-licking number induced by heat or formaldehyde and consequently had alleviating effect on pain in mice induced by chemicals and inflammatory reaction.Conclusion: Total flavonoids from the root bark of Morus alba have obvious antioxidant and analgesic activities.

关键词

桑白皮/总黄酮/镇痛/抗氧化

Key words

Morus alba/flavonoids/analgesia activity/antioxidant activity

分类

农业科技

引用本文复制引用

崔珏,李超,姜中生..桑白皮总黄酮的抗氧化与镇痛活性研究[J].食品科学,2011,32(23):281-284,4.

基金项目

徐州工程学院培育项目 ()

食品科学

OA北大核心CSCDCSTPCD

1002-6630

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