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黄芪多糖对2型糖尿病大鼠NGFmRNA表达的影响

刘洪凤 崔荣军 申梅淑 韩智学

中国食物与营养2011,Vol.17Issue(8):66-67,2.
中国食物与营养2011,Vol.17Issue(8):66-67,2.

黄芪多糖对2型糖尿病大鼠NGFmRNA表达的影响

Effect of Astragalus Polysaccharides on Expression of Nerve Growth Factor Gene of Cerebrum in Type 2 Diabetic Rats

刘洪凤 1崔荣军 1申梅淑 1韩智学1

作者信息

  • 1. 黑龙江省牡丹江医学院生物化学教研室,黑龙江牡丹江157011
  • 折叠

摘要

Abstract

[Objective] To study the effect of astragalus polysaccharides on the expression of the brain nerve growth factor mRNA in type 2 diabetic rats. [Method] To select type 2 diabetic rats with gastric filling of various dosage of astragalus polysaccharides and physiological saline, 10 rats in each group and 10 normal rats as control, the expression of brain NGF mRNA was measured with by RT-PCR. [Result] The mRNA expression of brain NGF in type 2 diabetic groups was lower than that of normal group, and the astragalus polysaccharides groups were higher than that of type 2 diabetic model. [Conclusion] Astragalus polysaccharides could increase the mRNA expression of brain NGF in type 2 diabetic rats.

关键词

黄芪多糖/2型糖尿病大鼠/神经生长因子/基因表达

Key words

astragalus polysaccharides/type 2 diabetic rat/NGF/mRNA expression

分类

生物科学

引用本文复制引用

刘洪凤,崔荣军,申梅淑,韩智学..黄芪多糖对2型糖尿病大鼠NGFmRNA表达的影响[J].中国食物与营养,2011,17(8):66-67,2.

基金项目

:黑龙江省教育厅科学技术研究项目(项目编号:11551523). ()

中国食物与营养

OACSTPCD

1006-9577

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