响应面法优化芫花总黄酮的提取工艺OA北大核心CSTPCD
Optimization of reflux extraction of total flavonoids from genkwa flos using response surface analysis
以乙醇为溶剂,采用回流提取的方法,建立芫花中总黄酮类物质的最佳提取工艺.在单因素实验的基础上,运用四因素三水平的 Box - Behnken 中心组合试验设计原理进行实验设计,建立提取温度、提取时间、乙醇浓度、料液比与芫花总黄酮得率之间的数学模型.该模型的响应面分析结果表明,所建立的回归方程极显著,拟合性好.在总的作用因素中,平方项对总黄酮的得率的影响最为显著,其次为一次项,交互项的影响相对较小.在回流提取条件下,乙醇浓度对总黄酮得率的影响最大,…查看全部>>
An optimal reflux extraction of total flavonoids from genkwa flos was established. Based on the single factor analysis, a 4 - factor, 3 - level Box - Behnken experimental design was applied to evaluate the effects of the four factors , including extraction temperature, extraction time, ethanol concentration and ratio of material to liquid. The interactions of each factor on the extraction yield were investigated with response surface analysis ( RSA). Results…查看全部>>
邓仕任;夏林波;李博
辽宁中医药大学药学院,大连116600辽宁中医药大学药学院,大连116600辽宁中医药大学药学院,大连116600
轻工纺织
芫花总黄酮回流提取响应面分析
genkwa flos total flavonoids reflux extraction response surface analysis
《中国食品添加剂》 2012 (1)
70-75,6
国家"十一五"科技支撑计划课题(2006BA109B06-07-1),辽宁中医药大学优秀青年药学人才基金(yxrc0916).
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