食品工业科技2012，Vol.33Issue(4)：393-395,3.
海苔发酵提取物对原发性高血压大鼠的降压效果研究
Study on effect of Porphyra extract on blood pressure in spontaneously hypertensive rats
摘要
Abstract
We used Lactobacillus brevis that could produce GABA to ferment Porphyra and we got the Porphyra extract（Pe）,containing 10.5% γ-aminobutyric acid（GABA）.The effect of Porphyra extract on blood pressure in spontaneously hypertensive rats（SHRs） was examined.A single medication at different doses of Porphyra extract（2mg/kg·bw and 0.2mg/kg·bw） were intragastic administered.After administration,blood pressure was measured at 2,5,9,24h.And the dose of Pe（2mg/kg·bw of rat weight） in SHRs showed a significant reduction in systolic blood pressure compared to the control group（p0.05,p0.01）.While long term medication,groupth phase SHRs and gerontic SHRs were separately fed a diet containing Pe at the level of 0.003% and 0.001%.After administration,blood pressure and body weight were determined every 2 or 3 days.Finally,groupth phase SHRs and gerontic SHRs at the level of 0.003% also showed a significantly lowered blood pressure compared to the control group（p0.01,p0.05）.关键词
海苔/γ-氨基丁酸（GABA）/原发性高血压大鼠（SHR）/降压Key words
Porphyra/γ-aminobutyric acid（GABA）/spontaneously hypertensive rats（SHRs）/hypertensive effect分类
轻工纺织引用本文复制引用
王娅,梅川逸人,蔡健荣,骆琳,丁青芝..海苔发酵提取物对原发性高血压大鼠的降压效果研究[J].食品工业科技,2012,33(4):393-395,3.基金项目
国家自然基金 （）
江苏省科技支撑计划-农业部分 （）
