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硝酸酯类槲皮素衍生物的制备及抗氧化活性研究

韦静 李芳耀 杨新平 文杜鹃 邓海东

食品工业科技2012,Vol.33Issue(5):95-96,100,3.
食品工业科技2012,Vol.33Issue(5):95-96,100,3.

硝酸酯类槲皮素衍生物的制备及抗氧化活性研究

Study on preparation and antioxidant activity of quercetin derivatives coupled with nitrate moiety

韦静 1李芳耀 2杨新平 2文杜鹃 2邓海东2

作者信息

  • 1. 桂林医学院研究生学院,广西桂林541004
  • 2. 桂林医学院药学院,广西桂林541004
  • 折叠

摘要

Abstract

Two novel quercetin derivatives coupled with nitrate moiety were prepared with alkylene dibromide and AgNO3 from quercetin.Their structures were characterized by 1H-NMR and ESI-MS.Their capability of scavenging the DPPH· and·OH radicals were evaluated.The preliminary assay results showed that the products possessed strong scavenging activity on reducing power on DPPH· and ·OH radicals with maximum scavenging rate 88.7%,90.1% and 78.6%,80.6%,effectively scavenged DPPH· and ·OH radicals with IC50 of 4.2,4.5mg/L and 19.2,22.3mg/L,respectively.

关键词

槲皮素/抗氧化活性/衍生物

Key words

quercetin/antioxidant activity/derivative

分类

轻工纺织

引用本文复制引用

韦静,李芳耀,杨新平,文杜鹃,邓海东..硝酸酯类槲皮素衍生物的制备及抗氧化活性研究[J].食品工业科技,2012,33(5):95-96,100,3.

基金项目

广西教育厅科研立项项目 ()

桂林医学院青年教师科研启动基金 ()

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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