食品科学2012，Vol.33Issue(3)：252-255,4.
鮟鱇鱼骨对去卵巢骨质疏松大鼠的影响
Effects of Lophius litulon Bone in Ovariectomized Rats with Osteoporosis
摘要
Abstract
Purpose： To find out the effect ofLophius litulon bone on osteoporosis in ovariectomized rats. Methods： Sixty SD female rats were divided at random into six groups： sham-operation group, model control group, positive control group [1000 mg/（kg·d） calcium lactate] and low-, medium- and high-dose treatment groups [at the doses of 665, 2100 mg/（kg od） and 6636 mg/（kg· d）, respectively]. At 12 days after ovariectomy, the rats were administrated for 12 consecutive weeks and then killed for the determination of femoral length and weight, uterus shape, and the serum levels of Ca, P, APL, AST and ALT. Results： The three treatment groups showed an increase in femoral weight compared with the model control group, but no significant difference in femoral length and the serum levels of P and Ca was observed. The serum levels of APL, AST and ALT in the model control group were significantly higher those of the sham-operation group, but no significant difference existed among the treatment groups and sham-operation group. In addition, each treatment group could promote endometrial gland development and microvillar growth in endometrial gland nonciliated epithelial cells. Conclusion： Lophius litulon bone can improve the serum biochemical indices and promote microvillar growth in endometrial gland nonciliated epithelial cells.关键词
鮟鱇鱼骨/去卵巢大鼠/子宫形态/生化指标Key words
Lophius litulon bone： ovariectomized rat： uterus shape： biochemical indices分类
轻工纺织引用本文复制引用
芦红艳,李妍妍,王奇,王霞,苏秀榕..鮟鱇鱼骨对去卵巢骨质疏松大鼠的影响[J].食品科学,2012,33(3):252-255,4.基金项目
宁波市科技局农业与社发领域重大科技项目 （）
宁波市重点学科资助项目 （）
