食品科学2012，Vol.33Issue(7)：247-250,4.
浒苔对营养性肥胖小鼠减肥功能的研究
Effect of Enteromorpha on Body Weight Loss in Nutritionally Obese Mice
摘要
Abstract
Objective： To explore the body weight-reducing effect of Enteromorpha in nutritionally obese mice. Methods： A nutritionally obese mouse model was established by oral administration of a nutritional diet. The mice were divided into five groups including model group （T-cont group）, Enteromorpha groups at high, medium and low dosages （T-high group, T-med group and T-low group） and positive control group （P-cont group）. The mice from T-cont group were fed a basal diet. The mice from T-high group, T-med group and T-low group were fed a basal diet with the addition of 30%, 20% and 10% Enteromorpha, respectively. The mice from P-cont group were fed a basal diet supplemented with L-carnitine at 50 mg/（100 g· d）. After administration for 49 days, blood was drawn from mouse eyeballs. The contents of serum TC, TG, LDL-C and HDL-C, the activities of serum ALT and AST, body weight, Lee＇s index and fat coefficient were evaluated. Results： Enteromorpha at high, medium and low dosages and L-carnitine could significantly decrease body weight, Lee＇s index and fat coefficient, the contents of serum TC, TG and LDL-C and the activities of serum ALT and AST, and increase HDL-C content and I-IDL-C/TC ratio in male and female nutritionally obese mice. Conclusion： Enteromorpha has obvious weight loss function. Its possible mechanisms may be involved in the suppression of fat accumulation, regulation of blood lipid and protection of liver function.关键词
浒苔/营养性肥胖/减肥Key words
Enteromorpha/nutritional obesity/weight loss分类
医药卫生引用本文复制引用
禹海文,李妍妍,苏秀榕..浒苔对营养性肥胖小鼠减肥功能的研究[J].食品科学,2012,33(7):247-250,4.基金项目
浙江省科技厅重大科技攻关项目 （）
