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黄连生物碱降低卷烟主流烟气中苯并[α]芘的研究

吴金凤 李学刚 戴亚 朱立军 谭兰兰

食品工业科技2012,Vol.33Issue(12):102-105,4.
食品工业科技2012,Vol.33Issue(12):102-105,4.

黄连生物碱降低卷烟主流烟气中苯并[α]芘的研究

Study on the effect of coptis alkaloids on the decrease of benzo [α] pyrene in cigarette smoke

吴金凤 1李学刚 2戴亚 3朱立军 3谭兰兰3

作者信息

  • 1. 西南大学药学院,重庆400716 重庆烟草工业有限责任公司重庆卷烟厂,重庆400061
  • 2. 西南大学药学院,重庆400716
  • 3. 川渝中烟工业公司技术研发中心,四川成都610066
  • 折叠

摘要

Abstract

For reducing the content of benzo[α]pyrene(B[α]P) in the mainstream cigarette smoke(MSS),a novel filter additive containing the plant alkaloid was studied.Coptis alkaloids were extracted from rhizome of coptis chinensis,which contained a lot of the quaternary ammonium hydrate with isoquinoline structure.The interactions of coptis alkaloids with B[α]P was investigated by fluorescence quenching.The way of adding coptis alkaloids in the cigarette filter to reducing B[α]P were discussed.The results showed that the correlation coefficients of coptis alkaloids and B[α]P were 0.981~0.998,and the binding constants were(2.0~9.0)×103,more than 20% of B[α]P were eliminated from MSS,with greater reductions when more coptis alkaloids were added in the filter.With the same mass of coptis alkaloids in the filter,the reduction trend for B[α]P was palmatine〉coptis total alkaloids〉berberine〉coptisine.Comparing with the control cigarette,the content of B[α]P in the mainstream smoke of cigarette with palmatine in modified filter were reduced by 25.16%,when the filter containing 120mg/g of palmatine carried by 15mg/cig of activated carbon fiber.

关键词

卷烟/黄连生物碱/烟气/苯并[α]芘

Key words

cigarette/coptis alkaloids/smoke/benzo[α]pyrene

分类

轻工纺织

引用本文复制引用

吴金凤,李学刚,戴亚,朱立军,谭兰兰..黄连生物碱降低卷烟主流烟气中苯并[α]芘的研究[J].食品工业科技,2012,33(12):102-105,4.

食品工业科技

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