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四株益生菌对高脂血症仓鼠降血脂作用的研究

张泽生 王俊辉 李健 赵春晓

食品工业科技2012,Vol.33Issue(12):365-367,381,4.
食品工业科技2012,Vol.33Issue(12):365-367,381,4.

四株益生菌对高脂血症仓鼠降血脂作用的研究

Hypolipidemic effects of four probiotic strains in hyperlipidemic hamsters

张泽生 1王俊辉 1李健 1赵春晓1

作者信息

  • 1. 天津科技大学食品工程与生物技术学院,天津300457
  • 折叠

摘要

Abstract

Objective:To observe influence of different probiotic strains on lipid metabolism of experimental hyperlipidemic hamsters.Methods:Healthy male hamsters were fed high-fat diet to create the hyperlipidemic animal model.Probiotic liquid were filled into stomach of hamsters.The content of total cholesterol(TC),triglyceride(TG),high-density lipoprotein cholesterol(HDL-C)in serum and total cholesterol,triglyceride in liver were assayed.Results:The TC,TG,non-high density lipoprotein cholesterol(non-HDL-C)and the value of atherosclerosis index(AI)in serum could be decreased significantly in the hyperlipidemic hamsters by four probiotic strains.The HDL-C in serum could be increased.The TC,TG in lipid could also be decreased.Conclusion:Lipid metabolism of hamsters could be improved,and the incidence of atherosclerosis could also be prevented and reduced by four probiotic strains.The ability of Lactobacillus rhamnosus reducing TC,TG in serum was the strongest,the ability of Lactobacillus acidophilus as well as Lactobacillus rhamnosus increasing HDL-C in serum and Lactobacillus acidophilus lowering TC in liver was the strongest.

关键词

益生菌/高脂血症/仓鼠

Key words

probiotic/hyperlipidemia/hamster

分类

轻工纺织

引用本文复制引用

张泽生,王俊辉,李健,赵春晓..四株益生菌对高脂血症仓鼠降血脂作用的研究[J].食品工业科技,2012,33(12):365-367,381,4.

基金项目

天津市高等学校科技发展基金计划项目 ()

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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