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滁菊总黄酮对大鼠急性心肌缺血保护作用的实验研究

俞浩 周国梁 刘汉珍 周金星 杨剑婷

食品工业科技2012,Vol.33Issue(13):352-354,358,4.
食品工业科技2012,Vol.33Issue(13):352-354,358,4.

滁菊总黄酮对大鼠急性心肌缺血保护作用的实验研究

Study on the effect of chuju total flavonoids on actue myocardial ischemia in rats

俞浩 1周国梁 1刘汉珍 1周金星 1杨剑婷1

作者信息

  • 1. 安徽科技学院食品药品学院,安徽凤阳233100
  • 折叠

摘要

Abstract

Objective.To observe the effect of chuju total flavonoid on acute myocardial ischemia in rats. Methods: The rats model of acute myocardial infarction were induced by ligating anterior branch of the left coronary artery. The II lead electrocardiograms and the infarction area of myocardium were analyzed,the activities of LDH,CK and SOD in serum were assayed,the concentration of MDA,TXB2 and 6-Keto-PGF1α in serum were also determined. Results.Chuju total flavonoid could obviously refrain the elevated J of ECG,decrease the infarction area of myocardium,increase the activity of SOD and the concentration 6-keto-PGF1α,reduce the activities of CK,LDH and the concentrstion of MDA and TXB2 in serum comparing with model rats(p〈0.05 or p〈0.01 ).Conclusion.Chuju total flavonoid has the protective effect on acute myocardial ischemia in rats.

关键词

滁菊总黄酮/大鼠/急性心肌缺血/脂质过氧化/血小板功能

Key words

chuju total flavonoid/rat/acute myocardial infarction lipid peroxidation/platelet function

分类

轻工纺织

引用本文复制引用

俞浩,周国梁,刘汉珍,周金星,杨剑婷..滁菊总黄酮对大鼠急性心肌缺血保护作用的实验研究[J].食品工业科技,2012,33(13):352-354,358,4.

基金项目

安徽省自然科学基金项目 ()

科技部科技人员服务企业行动项目 ()

安徽科技学院稳定人才项目(ZRC2011297). ()

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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