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两种异硫氰酸酯抗肿瘤的研究进展

陈楠 任凌燕 戴传云

食品与机械2012,Vol.28Issue(2):241-244,4.
食品与机械2012,Vol.28Issue(2):241-244,4.

两种异硫氰酸酯抗肿瘤的研究进展

Research advances on two kinds of isothiocyanates for cancer chemoprevention

陈楠 1任凌燕 1戴传云1

作者信息

  • 1. 重庆科技学院化学化工学院生物与制药系,重庆401331
  • 折叠

摘要

Abstract

The biological function of phytochemicals has became one of the hottest research areas on food science . For the cancer chemopre~ vention , isothiocyanates 2-Phennethyl(PEITC) and 4-Methylsulfi-nylbuty(SFN) from the crucifers were widely investigated. These anti-cancer activities have been attributed to a variety of physiological actions including inducing phase I and phase fl enzymes, activating Nrf2-Keapl system , inhibiting the transcription factor k b and promoting cell apoptosis. Their molecular mechanisms of chemopreven-tion effects and perspectives were reviewed in this paper which amid to provide reference for the cruciferaes resource development.

关键词

2-苯乙基异硫氰酸酯/1-异硫氰酸-4-甲磺酰基丁烷/抗肿瘤/分子机制

Key words

2-Phennethyl/4-MethytsulfinyIbuty/anticancer/ molecular mechanisms

引用本文复制引用

陈楠,任凌燕,戴传云..两种异硫氰酸酯抗肿瘤的研究进展[J].食品与机械,2012,28(2):241-244,4.

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