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黄芪多糖对2型糖尿病大鼠心肌细胞钙通道基因表达的影响研究

刘洪凤 王桂云 张杰 韩智学

中国食物与营养2012,Vol.18Issue(5):61-62,2.
中国食物与营养2012,Vol.18Issue(5):61-62,2.

黄芪多糖对2型糖尿病大鼠心肌细胞钙通道基因表达的影响研究

Influence of APS on the Calcium Channel Gene Expression in Cardiomyocyte of Type 2 Diabetes Rats

刘洪凤 1王桂云 1张杰 1韩智学1

作者信息

  • 1. 牡丹江医学院生物化学教研室,黑龙江牡丹江157011
  • 折叠

摘要

Abstract

[Objective] To investigate the influence of APS on the L-type calcium channel protein mRNA expression of the cardiomyocyte in the type 2 diabetes rats. [Method] Wistar rats were randomly divided into the control group, model group and APS groups. The mRNA expression of L-type calcium channelprotein was metered by RT-PCR at the end of 8 weeks. [Result] The expressions of the L-type calcium protein mRNA of diabetes group and therapy group were significantly higher than that of the control group, while the therapy group was significantly lower than the model group (P〈0.01). [Conclusion] APS can decrease the L-type calcium channel protein mRNA expression in the cardiomyocyte of the type 2 diabetes rats. APS have therapeutic effect on type 2 diabetes.

关键词

黄芪多糖/2型糖尿病/L型钙通道基因

Key words

APS 2-DM L-type calcium channel protein mRNA

分类

生物科学

引用本文复制引用

刘洪凤,王桂云,张杰,韩智学..黄芪多糖对2型糖尿病大鼠心肌细胞钙通道基因表达的影响研究[J].中国食物与营养,2012,18(5):61-62,2.

基金项目

黑龙江省教育厅科学技术研究项目(项目编号:11551523). ()

中国食物与营养

OACSTPCD

1006-9577

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