Culture supernatants of breast cancer cell line MDA-MB-231 treated with parthenolide inhibit the proliferation, migration, and lumen formation capacity of human umbilical vein endothelial cellsOACSCDCSTPCD
Culture supernatants of breast cancer cell line MDA-MB-231 treated with parthenolide inhibit the proliferation, migration, and lumen formation capacity of human umbilical vein endothelial cells
Background Parthenolide has been tested for anti-tumor activities,such as anti-proliferation and pro-apoptosis in recent studies.However,little is known about its role in the process of tumor angiogenesis.This study aims to investigate the effects and potential mechanisms of parthenolide on the proliferation,migration and lumen formation capacity of human umbilical vein endothelial cells.Methods Different concentrations of parthenolide were applied to the hu…查看全部>>
LI Cai-juan;GUO Su-fen;SHI Tie-mei
Department of Ultrasound,Hongqi Hospital of Mudanjiang Medical University,Mudanjiang,Heilongjiang 157001,ChinaDepartment of Ultrasound,Shengjing Hospital,China Medical University,Shenyang,Liaoning 110004,ChinaDepartment of Pathology,Mudanjiang Medical University,Mudanjiang,Heilongjiang 157011,China
parthenolideMDA-MB-231 cellshuman umbilical vein endothelial cellsangiogenesis
parthenolideMDA-MB-231 cellshuman umbilical vein endothelial cellsangiogenesis
《中华医学杂志(英文版)》 2012 (12)
2195-2199,5
评论