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红曲菌的复合诱变及其固态发酵条件的优化

杨欢欢 胡中泽

食品科学2012,Vol.33Issue(11):247-251,5.
食品科学2012,Vol.33Issue(11):247-251,5.

红曲菌的复合诱变及其固态发酵条件的优化

Combined Mutation of Monascus and Optimization of Fermentation Conditions for Monacolin K Production

杨欢欢 1胡中泽1

作者信息

  • 1. 武汉工业学院食品科学与工程学院,湖北武汉430023
  • 折叠

摘要

Abstract

A strain of Monascus purpureu was treated with UV irradiation and its spore was then incubated in media containing LiCl to induce mutation.A mutant strain with high yield of monacolin K was obtained and its fermentation conditions were optimized for monacolin K production.The results showed that the optimal fermentation conditions were initial temperature of 30 ℃,late temperature of 24 ℃ and original moisture content of germinated brown rice of 60%.Under these conditions,the yield of monacolin K reached 5.33 mg/g.

关键词

红曲菌/复合诱变/Monacolin/K/响应面

Key words

Monascus/combined mutation/monacolin K/response surface methodology

分类

生物科学

引用本文复制引用

杨欢欢,胡中泽..红曲菌的复合诱变及其固态发酵条件的优化[J].食品科学,2012,33(11):247-251,5.

基金项目

湖北省自然科学基金重点项目 ()

食品科学

OA北大核心CSCDCSTPCD

1002-6630

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