食品工业科技2012,Vol.33Issue(10):343-346,4.
鹿茸醇提物对小鼠学习记忆功能的影响
Effect of antler velvet alcohol extracts on improving learning and memory sbilities in mice
摘要
Abstract
Objective:To investigate the effect of antler velvet alcohol extract(AVAE)on learning and memory in mice.Methods:One hundred and fifty-six male Kunming mice were randomized into control group(12 mice,given salty water),memory obtain stage group,memory consolidate stage group and memory reappearance stage group(48 mice in each group),each group had 3 small groups:high dose,mid dose and low dose group,given alcohol extract of antler velvet dry matter on 1kg/(kg·d),0.5kg/(kg·d)and 0.1kg/(kg·d)respectively.After 30d,each stage's latency and number of errors of jumping platform experiment as well as swimming time and number of errors of water maze were tested,at the same time,the activity of SOD and the content of MDA in mind were evaluated.Results:The AVAE could prolong the latency(P0.01)of jumping platform experiment on each stage as well as decreasing the number of errors(P0.01)obviously,and decrease the swimming time and the number of errors(P0.01,P0.05)of water maze,then increase the activity of SOD(P0.01,P0.05)and decrease the content of MDA in mice brain(P0.01,P0.05).Conclusions:The AVAE had the function of improving learning and memory impairment obviously.关键词
鹿茸醇提物/学习记忆/跳台实验/水迷宫实验Key words
antler velvet alcohol extract(AVAE)/learning and memory/jumping platform experiment/water maze experiment分类
轻工纺织引用本文复制引用
赵玉红,张睿,潘强..鹿茸醇提物对小鼠学习记忆功能的影响[J].食品工业科技,2012,33(10):343-346,4.基金项目
黑龙江省教育厅科学技术研究指导项目 ()
东北林业大学研究生创新项目 ()