食品与发酵工业2012，Vol.38Issue(4)：53-56,4.
雪白白僵菌产环孢菌素A分批补料发酵动力学
Fed-batch Fermentation Kinetics of Cyclosporine A by Beauveria nivea
摘要
Abstract
The kinetic models of the fed-batch fermentation of cyclosporin A in 301 bioreactor were studied. Based on the fed-batch fermentation data and Logistic model, the kinetics models of cyclosporin A fermentation for cell growth, cyclosporin production and substrate consumpsion were built up. The program of origin 7.5 version was used to fit the model. The analysis results showed that the good agreement of predicted values with the experimental values, and that the kinetic models could provide reasonable descriptions for the process of cyclosporin A fed-batch fermenta- tion. The development of fed-batch fermentation kinetics of cyclosporine A would help to regular the fermentation of cyclosporine A and increase the fermentation titer.关键词
雪白白僵菌/环孢菌素A/补料分批发酵/Origin程序Key words
Beauveria nivea/Cyclosporin A/fed-batch fermentation/origin program分类
化学化工引用本文复制引用
姜俊云,董惠钧,闫同顺..雪白白僵菌产环孢菌素A分批补料发酵动力学[J].食品与发酵工业,2012,38(4):53-56,4.基金项目
2007年度国家科技支撑计划项目 （）
