食品与机械2012，Vol.28Issue(4)：113-116,4.DOI:10.3969/j.issn.1003-5788.2012.04.031
荔枝核提取物及其阳离子树脂分离物体外降血糖作用
Hypoglycemic effect in vitro of litchi seed extract and its fraction by cation exchange resin
徐婷 1吴青 2高骏伟1
作者信息
- 1. 华南农业大学食品学院,广东广州510640
- 2. 广东省食品质量安全重点实验室,广东广州 510640
- 折叠
摘要
Abstract
The hypoglycemic effects of the litchi seed extract (LSE) and fraction by cation exchange resin(FCE) were investigated. LSE or FCE with different concentration was cultured with high glucose HepG2 cell model and insulin-resistant HepG2 cell model in vitro , u-sing the method of MTT and glucose assay kit to investigate the hypoglycemic effects. The results showed that on high glucose HepG2 cell model, LSE and FCE increased the glucose consumption of HepG2 cells, and FCE had higher effect compared with LSE at similar content. This revealed that fraction by cation exchange resin of litchi seed extract were attributed to the hypoglycemic effect. FCE also enhanced the glucose consumption in synergism with insulin. On insulin-resistant HepG2 cell model, FCE significantly reduced the insulin resistance, increasing the glucose consumption of HepG2 cells. These results suggested that LSE and FCE exhibited the hypoglycemic effect in vitro.关键词
荔枝核/树脂分离/降血糖/HepG2细胞模型/胰岛素抵抗模型Key words
litchi seed/ resin separation/ hypoglycemic/ HepG2 cell model/insulin-resistant cell model引用本文复制引用
徐婷,吴青,高骏伟..荔枝核提取物及其阳离子树脂分离物体外降血糖作用[J].食品与机械,2012,28(4):113-116,4.
