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蛹虫草发酵产虫草素的培养条件研究

汤佳鹏 柳依婷 赵强 董伟 朱俐

食品工业科技2012,Vol.33Issue(21):181-183,187,4.
食品工业科技2012,Vol.33Issue(21):181-183,187,4.

蛹虫草发酵产虫草素的培养条件研究

Study on culture condition ot cordycepin from Cordyceps militaris fermentation

汤佳鹏 1柳依婷 1赵强 1董伟 1朱俐1

作者信息

  • 1. 南通大学航海医学研究所生化与药学研究室,江苏南通226001
  • 折叠

摘要

Abstract

Effects of exogenous additives, such as wheat bran, corn cob and adenosine on cordycepin production in a submerged culture of Cordyceps militaris were investigated. The results showed that the addition of 3g/L of adenosine on the fifth day of fermentation was superior to other day.When addition amount of adenosine exceeds 4g/L,the yield of cordycepin on adenosine was about 25% and the maximal cordycepin production reached 1.6g/L The dynamics between growth of mycelium and the cordycepin synthesis were analyzed.The fermentation was mixed-growth associated.The optimum values for cordycepin production were shaken for 4d followed by 7d static culture. The maximum cordycepin production and productivity reached 1.60g/L and 145.5mg/L/d, respectively.It was indicated that the new culture technology obtained in this work possessed a high potential for the industrial production of cordycepin of Cordyceps militaris.

关键词

蛹虫草/虫草素/腺苷/振荡-静置培养

Key words

Cordyceps militaris/cordycepin/adenosine/shake- static culture

分类

化学化工

引用本文复制引用

汤佳鹏,柳依婷,赵强,董伟,朱俐..蛹虫草发酵产虫草素的培养条件研究[J].食品工业科技,2012,33(21):181-183,187,4.

基金项目

江苏省自然科学基金 ()

南通市应用研究计划(AS2011021). ()

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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