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食物源ACE抑制肽的生产及构效关系研究进展

王灵芝 张燕玲 王元明 乔延江

食品科学2012,Vol.33Issue(15):314-317,4.
食品科学2012,Vol.33Issue(15):314-317,4.

食物源ACE抑制肽的生产及构效关系研究进展

A Review of Angiotensin Converting Enzyme (ACE) Inhibitory Peptides Derived from Foods: Production and Quantitative Structure-Activity Relationship

王灵芝 1张燕玲 1王元明 1乔延江1

作者信息

  • 1. 北京中医药大学中药学院,北京100102
  • 折叠

摘要

Abstract

Bioactive peptides are peptides with physiological functions in the body,such as immunomodulatory,antimicrobial,anticancer,antivirus,antithrombotic and antihypertension functions.Currently,peptides from foods with angiotensin converting enzyme(ACE) inhibitory activity are the focus of intense study.ACE plays a vital role in the regulation of blood pressure by producing potent vasoconstrictor angiotensine II,as well as by inactivating the vasodilating bradykinin.ACE inhibitory peptides have widely been produced by gastrointestinal digestion,fermentation and maturation process,enzymatic hydrolysis and genetic recombination.These inhibitory peptides may be incorporated into functional foods and several products are currently commercially available or under development.This paper presents an overview of antihypertensive peptides derived from food protein.

关键词

生物活性肽/血管紧张素转化酶(ACE)/高血压

Key words

bioactive peptides/angiotensin converting enzyme(ACE)/hypertension

分类

生物科学

引用本文复制引用

王灵芝,张燕玲,王元明,乔延江..食物源ACE抑制肽的生产及构效关系研究进展[J].食品科学,2012,33(15):314-317,4.

基金项目

国家自然科学基金项目 ()

食品科学

OA北大核心CSCDCSTPCD

1002-6630

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