食品科学2012，Vol.33Issue(16)：159-162,4.
亲水作用色谱串联质谱同时检测食品接触产品中三聚氰胺和三聚氰酸单体迁移量
Simultaneous Determination of Melamine and Cyanuric Acid in Food Contact Packaging Materials by Hydrophilic Liquid Chromatography-Tandem Mass Spectrometry
摘要
Abstract
An HILC-MS/MS method was developed to simultaneously determine melamine and cyanuric acid in food contact packaging materials. Samples were extracted with 1-120, 4% acetic acid （V/V）, 10% ethanol isooctane （V/V） and olive oil separately, kept in a 70 ℃ incubator for 2 h and then filtered through a 0.2 μm microporous membrane prior to injection into an HILC-MS/ MS system. Melamine and cyanuric acid were separated, identified and quantified on HILC column by gradient mobile phase and monitored in a positive/negative electrospray ionization and multiple reaction monitor （MRM） mode. A good linear range was achieved over the concentration range of 1 -- 100 ng/mL and 2 -- 200 ng/mL for melamine and cyanuric acid in different stimulants, respectively. The limits of detection and limits of quantification were in the range of 0.4--0.8 ng/mL. The recovery rates of melamine and cyanuric acid were 134.0% --86.2% and 156.0%- 78.9% with RSDs of 6.44% -- 17.93% and 5.95%- 11.78%. This method was simple, rapid, and accurate, and suitable for the determination of melamine and cyacuric acid in food contact packaging materials.关键词
亲水作用色谱串联质谱/食品接触产品/三聚氰胺/三聚氰酸/迁移Key words
HILC-MS/MS/food contact packaging materials/melamine/cyanuric acid/migration分类
化学化工引用本文复制引用
吕水源,井伟,李小晶,江晓芬,刘正才,唐熙,陈旻实,陈锦权..亲水作用色谱串联质谱同时检测食品接触产品中三聚氰胺和三聚氰酸单体迁移量[J].食品科学,2012,33(16):159-162,4.基金项目
福建省科技计划重点项目 （）
国家质量监督检验检疫总局2011年度科技计划项目 （）
福建出入境检验检疫局科技计划项目 （）
