食品科学2012，Vol.33Issue(17)：279-283,5.
食物过敏原构象性表位鉴别的研究进展
Research Progress in Conformational Epitope Mapping Approaches for Food Allergens
摘要
Abstract
Conformational epitope is an important type of epitope and plays a critical role in allergy. Epitope mapping is the core of allergen research. Today, there are three main conformational epitope mapping approaches, including conformational epitope prediction based on the amino acid comlx~sition and characteristics of linear epitopes, epitope mapping by phage display technique and bioinfomaatics, and conformational epitope mapping by spectroscopic analysis and parameters related to coupling with antibodies. The first two approaches are commonly used in conformational epitope mapping. As a more accurate approach, spectroscopy has not been used in this field until recently. These approaches allow for a better knowledge and understanding of conformafional epitopes in allergen research and also provide theoretical evidence for the mechanisms of action of conformational epitopes in allergy.关键词
食物过敏原/构象性表位/定位Key words
food allergen/conformational epitope/mapping分类
轻工纺织引用本文复制引用
李欣,陈红兵..食物过敏原构象性表位鉴别的研究进展[J].食品科学,2012,33(17):279-283,5.基金项目
教育部新世纪优秀人才支持计划项H （）
国家自然科学基金项H（30860220）：南昌大学食品科学与技术国家重点实验室目标导向项（SKLF-MB.201002）：南昌大学食品科学与技术重点实验室青年骨干基金项目 （）
