食品科学2012，Vol.33Issue(18)：226-231,6.
超高效液相色谱一串联质谱法测定10种食品中的阿维菌素类药物残留
Determination of Avemecfin Residues in 10 Foods by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry
摘要
Abstract
A reliable analytical method to determine 6 avermectin residues in 10 foods was developed using ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). Samples were extracted with acetonitrile, evaporated in a rotary evaporator until dryness, re-dissolved in a mixture of acetonitdle and water ( 1:9, V/V), cleaned up on a PEP- C118cartridge, blown under nitrogen gas until dryness, and then re-dissolved in acetonitrile prior to UPLC-MS/MS analysis by positive ion electros[tcay ionization (ESI+) in multiple reaction monitoring (MRM) mode. The calibration curves of 6 avermectins were linear in the concentration of 5 - 250μ/a g/kg (R2 〉 0.99). The average recovery rates at three spiked levels were 60% -- 99% with relative standard deviations (RSDs) of 0.2%- 8.9%. The quantification limits for 6 avermeOins (RsN ≥ 10) were slightly lower than 5.0 μ g/kg. This analytical method could meet the requirements for trace analysis.关键词
阿维菌素类药物/固相萃取/超高效液相色谱－串联质谱Key words
abamectSrm/solid phase extraction/ullra-high high performance liquid chromatography-tandem mass spectrometry分类
轻工纺织引用本文复制引用
张文娟,连庚寅,郭晓喜,杨小兰,宋欢..超高效液相色谱一串联质谱法测定10种食品中的阿维菌素类药物残留[J].食品科学,2012,33(18):226-231,6.基金项目
国家质检总局科研项目 （）
