食品科学2012,Vol.33Issue(19):295-297,3.
鹿花盘蛋白对乳腺增生模型小鼠作用研究
Immunoregulatory Effect of Deer Antler Base Proteins on Mammary Gland Hyperplasia in Mice
摘要
Abstract
Objective: To investigate the effect of deer antler base proteins on estrogen level and immune function in mice with mammary gland hyperplasia. Methods: Mouse models of mammary gland hyperplasia were established by combined injection of estradiol benzoate and progesterone. After administration with deer antler base proteins for 25 consecutive days, the mouse models were tested for serum estradiol level, uterus coeffi cient and immune organ coeffi cients. Results: In comparison with the model group, the treatment group showed a signifi cant reduction in serum estradiol level and uterus coeffi cient of mice with mammary gland hyperplasia (P<0.05) and a signifi cant increase in thymus coeffi cient and spleen coefficient (P<0.05). Conclusion: Deer antler base proteins regulate the secretion of estrogens and enhance immune function in mice.关键词
鹿花盘/蛋白/雌二醇/免疫功能Key words
deer antler base/protein/estradiol/immune function分类
轻工纺织引用本文复制引用
王莘,姚艳飞..鹿花盘蛋白对乳腺增生模型小鼠作用研究[J].食品科学,2012,33(19):295-297,3.基金项目
长春市科技局重大攻关项目(2008214) (2008214)