食品科学2012，Vol.33Issue(19)：363-366,4.
硒蛋白及其对巨噬细胞功能调节作用的研究进展
Research Progress in Selenoproteins and Their Modulatory Effects on Macrophage Functions
孙纳新 1王成华2
作者信息
- 1. 济南大学医学与生命科学学院，山东济南 250022
- 2. 山东省化工研究院，山东济南 250014
- 折叠
摘要
Abstract
Selenium can exert its physiological functions in the form of selenoproteins in immune system. Macrophages play a pivotal role in immune regulation and bacterial defense. Recently, it has been found by using mice fed on selenium-rich diets, gene knockout mice and monoclonal antibody technology that selenoproteins have signifi cant impact on redox status, migration and infl ammatory responses of macrophages. In this article, we review recent research advances in the effects of selenoproteins on redox level, walk characteristics and inflammation in macrophages at the molecular level. This review suggests that selenoproteins may have complicated molecular modulation mechanisms and prospect medicinal benefi ts.关键词
硒蛋白/巨噬细胞/氧化还原水平Key words
selenoprotein/macrophage/redox status分类
生物科学引用本文复制引用
孙纳新,王成华..硒蛋白及其对巨噬细胞功能调节作用的研究进展[J].食品科学,2012,33(19):363-366,4.
