中国食品学报2012，Vol.12Issue(10)：34-39,6.
1种凉茶饮料预防饮食诱导“上火”功效的人体观察
Clinical Investigation of the Preventive Effects of an Herbal Tea on Diet-induced Shang-huo
摘要
Abstract
Herbal tea has been widely used to prevent Shang-huo (rising fire) in China and Chinese communities abroad, although its clinical efficacy and physiological/biochemical mechanism have not yet been illuminated. This study used the roasted meat and deep-fried chips to induce the Shang-huo symptoms in 4 volunteers. A Canton-style herbal tea was employed to investigate its Shang—huo preventing effects, by evaluating the changes in blood cell counts and ratios, lymphocytes counts and ratios, and inflammation mediators. The levels of endotoxin, serotonin and melatonin in blood were accessed. The 'hot' diet induced some typical Shang—huo symptoms, I.e. Thirstiness and throat pain, while up-regulating the number of white blood cells (26.2%), neutrophils (36.3%) and its ratio, and the levels of endotoxin (23.8 pg/mL) and serotonin (21.5 ng/mL). The herbal tea removed the Shang-huo symptoms while down-regulated the diet—induced rise in cell counts and inflammation mediators, which implied the preventive effects of herbal tea on Shang huo. With the herbal tea, the increase of endotoxin was eliminated to 6.4pg/mL, and the serotonin was reduced by 119.3 ng/ mL. Furthermore, the herbal tea notably increased the concentration of serum melatonin. The effects of the herbal tea may attribute to several biochemical interactions, namely the inhibiting synthesis/secretion of serotonin, or increasing the conversion of serotonin to melatonin, easing the inflammation in gastrointestinal track and the reduction of endotoxin intake.关键词
预防上火/凉茶/炎症/5-羟色胺/内毒素Key words
prevent Shanghuo(rising fire)/ herbal tea/ inflammation/ serotonin/ endotoxin引用本文复制引用
柯李晶,郭静科,林希贤,刘树滔,饶平凡,周建武..1种凉茶饮料预防饮食诱导“上火”功效的人体观察[J].中国食品学报,2012,12(10):34-39,6.基金项目
国家自然基金面上项目资助(No.30973871) （No.30973871）
