食品工业科技2013，Vol.34Issue(1)：105-107,3.
一种胶原蛋白寡肽促进皮肤胶原蛋白与透明质酸合成的研究
Study on the effect of collagen oligopeptid on synthesis of hyaluronic acid and collagen
摘要
Abstract
To study the effect of collagen oligopeptid on cell proliferation and synthesis of hyaluronic acid in cultured human skin fibroblast cell, and the effect of collagen oligopeptid on type I collagen secretion of mouse skin. Proliferation viability was detected by WST-8 assay.ELISA was used to detect the secretion of hyaluronic acid of cultured human skin fibroblast Collagen oligopeptid were given to mice and D-galactosewere injected into mice for six weeks.Then,determine the type I collagen secretion of mouse skin.The results of the experiment showed that the collagen oligopeptidcould stimulate the human skin fibroblast proliferation ( p < 0.01 ), and increase the hyaluronic acid and type I collagen secretion(p<0.05).Collagen oligopeptid from tilapia fish scale could stimulate human skin fibroblast proliferation,and meanwhile increase type I collagen and hyaluronic acid secretion.关键词
胶原蛋白寡肽/Ⅰ型胶原蛋白/透明质酸Key words
collagen oligopeptid/type I collagen/hyaluronic acid分类
轻工纺织引用本文复制引用
宋芹,陈封政,颜军,郭晓强,姚倩,黄露萍,苟小军..一种胶原蛋白寡肽促进皮肤胶原蛋白与透明质酸合成的研究[J].食品工业科技,2013,34(1):105-107,3.基金项目
肉类加工四川省重点实验室开放基金项目(11-R07) （11-R07）
