北京工商大学学报：自然科学版2012，Vol.30Issue(6)：40-44,5.
2-乙基苯并噁唑的微波超声波辅助合成
Synthesis of 2-Ethylbenzoxazole Assisted with Microwave and Ultrasonic Wave
摘要
Abstract
2-Ethylbenzoxazole was synthesized and polyphosphoric acid (PPA)as the catalyst using assist 2-aminophenol and propionic acid as the reagents ed with microwave and ultrasonic wave. The influ- ences of mole ratio of catalyst to reactant, reaction temperature, and reaction time were investigated. The optimum technology found was microwave power 800 W, ultrasonic wave power 800 W, the mole ratio of propionic acid to 2-aminophenol in 5.5: 1, the mole ratio of PPA to 2-aminophenol in 0.52: 1, reaction temperature 130 ℃ , and reaction time 15 min. After extracted and distilled in vacuum, the concentration of product of 2-ethylbenzoxazole reached to 99.78% with the yield of 47.96 %. Compared to 2-methyl- benzoxazole, organoleptic characteristics of 2-ethylbenzoxazole was significantly different, which smelled green, salty, sweet, and cool. The structure of 2-ethylbenzoxazole was confirmed by IR, MS and 1H-NMR.关键词
2-乙基苯并噁唑/2-氨基苯酚/微波/超声波/香料/合成Key words
2-ethylbenzoxazole/2-aminophenol/microwave/ultrasonic wave/flavor/synthesis分类
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刘智军,张平,王石,谢建春,孙宝国..2-乙基苯并噁唑的微波超声波辅助合成[J].北京工商大学学报：自然科学版,2012,30(6):40-44,5.基金项目
北京工商大学本科生科研学术创新基金项目 （）
北京工商大学研究生科研学术创新基金项目 （）
北京市教委科技发展计划重点项目 （）
