食品工业科技2013，Vol.34Issue(5)：358-362,5.
食品污染物3-氯-1,2-丙二醇毒理作用的研究进展
Review on the toxicological effect of 3-Monochloropropane-1 ,2-diol in food contaminant
摘要
Abstract
3-Monochloropropane-12-diol(3-MCPD) is a well-known contaminant that has been detected in a wide range of foods,originally identified in foods prepared by hydrochloric acid hydrolysis.More recently,fatty acid esters of 3-MCPD,which could release free of 3-MCPD by hydrolysis,have been found in various types of foods, most notably high levels were measured in refined vegetable oils.Studies have been found that 3-MCPD have clear toxic effect with species and site specific in rodents.In this paper, the domestic and foreign toxicological researches were reviewed, which related to metabolic pathways of 3 - MCPD.The toxicity of 3 - MCPD were discussed in detail from the aspect of short-term toxicity, carcinogenicity, genotoxicity, reproductive toxicity, immunotoxicity,neurotoxicity.On these bases,further toxicological research directions were pointed out.关键词
3-氯-1,2-丙二醇/毒理/食品安全/进展Key words
3-Monochloropropane-1,2-diol/toxicology/food safety/progress分类
轻工纺织引用本文复制引用
白顺,孙建霞,邹飞雁,孙丛龙,白卫滨..食品污染物3-氯-1,2-丙二醇毒理作用的研究进展[J].食品工业科技,2013,34(5):358-362,5.基金项目
"十二五"863计划课题(2013AA102202) （2013AA102202）
国家自然科学基金(31201340) （31201340）
"十二五"国家科技支撑计划课题(2012BAK01B03). （2012BAK01B03）
