食品工业科技2013，Vol.34Issue(11)：350-352,3.
蛹虫草子实体多糖抗突变作用
Study on the anti-mutagenic effect of Cordyceps militaris polysaccharide
郭丽新 1冯哲 2魏博洋 3齐彦 2王世龙 2赵敏2
作者信息
- 1. 东北林业大学生命科学学院,黑龙江哈尔滨150040
- 2. 黑龙江中医药大学基础医学院,黑龙江哈尔滨150040
- 3. 西南科技大学生命科学与工程学院,四川绵阳621010
- 折叠
摘要
Abstract
To evaluate the effect of Cordyceps militaris polysaccharides(CMPS)on micronucleus formation rate of polychromatic erythrocyte (PCE)of bone marrow cells in mice and chromosome aberration rates induced by cyclophosphamide(CTX).Micronucleus test and chromosomal aberration test were carried out.The micronucleus inhibition rates were 29.75％,36.20％ and 44.48％ respectively in CMPS1,CMPS2 and CMPS3 group.Inhibition rates were increased with the dose increasing.Compared with the CTX group,each dose group were significantly different(p ＜ O.05).The aberration rates which were decreased with the dose increasing were 36.7％ ± 5.46％,20.8％±3.52％ and 18.1％ ±3.28％ respectively in CMPS1,CMPS2 and CMPS3 group.CMPS could reduce the micronucleus inhibition rates of PCE of bone marrow cells in mice and the aberration rates induced by CTX,CMPS had anti-mutagenic activity.关键词
蛹虫草多糖/微核/染色体畸变/环磷酰胺Key words
Cordyceps militaris polysaccharide/ micronucleus/ chromosome aberration/ cyclophosphamide分类
轻工纺织引用本文复制引用
郭丽新,冯哲,魏博洋,齐彦,王世龙,赵敏..蛹虫草子实体多糖抗突变作用[J].食品工业科技,2013,34(11):350-352,3.
