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诃子粗提物及不同极性部位抑制低密度脂蛋白氧化修饰的研究

刘仁绿 肖敏 江卫青 张良慧 廖亮 江慎华

食品工业科技2013,Vol.34Issue(16):100-104,5.
食品工业科技2013,Vol.34Issue(16):100-104,5.

诃子粗提物及不同极性部位抑制低密度脂蛋白氧化修饰的研究

Anti-low density lipoprotein oxidation of the crude extract and different fractions of Terminalia chebuLa Retz

刘仁绿 1肖敏 1江卫青 1张良慧 1廖亮 1江慎华1

作者信息

  • 1. 九江学院生命科学学院,江西九江332000
  • 折叠

摘要

Abstract

The property of anti-low density lipoprotein oxidation of Terminalia chebuLa Retz(TCR) was studied in vitro Cu2+ induction on LDL.The effective fraction of TCR on the anti-LDL oxidation was determined by thiobarbituric acid reactive substance (TBARS) guided method.All these results were showed as follows:The inhibition rates of the TCR crude extracts on LDL oxidation were 64.31%,77.22% and 82.66%,respectively.The ethyl acetate fraction possessed the most strong inhibition activity on LDL than other three fractions(p<0.05),and was the effective fraction with the same concentrations.The inhibition rates of the effective fraction (0.5,0.9 and 2.7mg/mL) were 73.19%,81.85% and 86.29%,respectively.The incubation periods of oxidation were delayed and degrees of oxidation were reduced by the effective fraction with different concentrations.The property of anti-low density lipoprotein oxidation of TCR was related to the total flavonoids and polyphenols in it.This study showed that TCR possessed strong anti-LDL oxidation activity and lay the foundation for further exploration on anti-atherosclerotic functional foods.

关键词

诃子/低密度脂蛋白/氧化修饰/硫代巴比妥酸反应物

Key words

Terminalia chebuLa Retz /low density lipoprotein /oxidative modification / thiobarbituric acid reactive substance

分类

轻工纺织

引用本文复制引用

刘仁绿,肖敏,江卫青,张良慧,廖亮,江慎华..诃子粗提物及不同极性部位抑制低密度脂蛋白氧化修饰的研究[J].食品工业科技,2013,34(16):100-104,5.

基金项目

中国博士后科学基金资助项目(20100481099) (20100481099)

江西省自然科学基金(20132BAB204030) (20132BAB204030)

江西省教育厅科技项目(GJJ12620) (GJJ12620)

江西省科技支撑计划(20123BBF60150) (20123BBF60150)

江苏省农产品物理加工重点实验室开放课题资助项目(JAPP2010-5). (JAPP2010-5)

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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