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榆耳发酵液多糖对小鼠免疫功能的影响

崔京春 郭海勇 邢效瑞 张献 屈天娇 胡东良 胡文忠 钱爱东 李玉

食品工业科技2013,Vol.34Issue(16):342-346,350,6.
食品工业科技2013,Vol.34Issue(16):342-346,350,6.

榆耳发酵液多糖对小鼠免疫功能的影响

Effect of polysaccharides from fermented Gloeostereum Incaratum on immune function in mice

崔京春 1郭海勇 2邢效瑞 3张献 1屈天娇 4胡东良 5胡文忠 1钱爱东 6李玉1

作者信息

  • 1. 大连民族学院生命科学学院,辽宁大连116600
  • 2. 吉林农业大学食药用菌教育部工程研究中心,吉林长春130118
  • 3. 吉林师范大学生命科学学院,吉林四平136000
  • 4. 吉林农业大学动物科学技术学院,吉林长春130118
  • 5. 大连吉翔农业科技有限公司,辽宁大连116620
  • 6. 北里大学兽医学部,青森十和田 0348628
  • 折叠

摘要

Abstract

To investigate the effect of polysaccharides from fermented gloeostereum incaratum on immune function in mice,after feeding with three different dosages (1,5 and 20mg/d) of polysaccharides from supemant of fermented Gloeostereum incaratum,spleen index,serum hemolysin level,phagocytosis rate of macrophages,proliferation rate of T lymphocytes and CD4+/CD8+ ratio were detected.Results showed that comparing with negative control of sterile water,all dosage groups had no effect on spleen index,the low dosage group could significantly increase phagocytosis rate of macrophages and proliferation rate of T lymphocytes,medium and high dosage groups could significantly(p<0.05) or extremely significantly(p<0.01) increaseserum hemolysin level,phagocytosis rate of macrophages,proliferation rate of T lymphocytes and CD4+/CD8+ ratio.These results indicated that polysaccharides from the supernatant of the fermented G.incamatum have strong immune enhancement effect in mice.

关键词

榆耳发酵液多糖/巨噬细胞吞噬率/T淋巴细胞转化率/CD4+/CD8+比值/小鼠

Key words

polysaccharides from fermented Gloeostereum incaratum/phagocytosis rate of macrophages/proliferation rate of T lymphocytes/ CD4+/CD8+ ratio/ mice

分类

轻工纺织

引用本文复制引用

崔京春,郭海勇,邢效瑞,张献,屈天娇,胡东良,胡文忠,钱爱东,李玉..榆耳发酵液多糖对小鼠免疫功能的影响[J].食品工业科技,2013,34(16):342-346,350,6.

基金项目

2011年度教育部"长江学者和创新团队发展计划"创新团队项目(IRT1134) (IRT1134)

吉林省教育厅"十二五"科学技术研究项目(吉教科合字2012178) (吉教科合字2012178)

大连民族学院博士启动金(20116205). (20116205)

食品工业科技

OA北大核心CSCDCSTPCD

1002-0306

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