茶叶科学Issue(2)：165-170,6.
普洱茶水提物与硝苯地平联用降压效果研究
Research on Combined Anti-hypertensive Effect of Pu'er Tea Extract and Nifedipine
李彦川 1李欣欣 1周王谊 1李长文 1马晓慧1
作者信息
摘要
Abstract
To explore combined anti-hypertensive effect of Pu'er tea extract and Nifedipine in SHR, 50 SHR rats were randomly divided into different model groups, N.L group, N.H group, N.L+D.L group and N.L+D.H group, 10 rats for each group. Wistar rats were selected as control group. Pu'er tea extract and Nifedipine were administered to SHR for 4 weeks. The blood pressure was measured once per week. Results showed that mean blood pressure was significantly reduced in spontaneous hypertension rats after treatment with 6.2 mg·kg-1 nifedipine, compared with model controls (P<0.05). The 3.1 mg·kg-1 nifedipine also has a tendency to decrease blood pressure. Combined antihypertensive effect of Pu'er tea extract and nifedipine was enhanced compared with nifedipine alone. The nifedipine showed anti-hypertensive effect on spontaneous hypertension rats in a dose-dependent manner. Pu'er tea extract can enhance the antihypertensive effect of nifedipine, and showed a certain degree of protective on heart.关键词
普洱茶水提物/硝苯地平/自发性高血压大鼠Key words
Pu'er tea extract/nifedipine/spontaneous hypertension rats分类
轻工纺织引用本文复制引用
李彦川,李欣欣,周王谊,李长文,马晓慧..普洱茶水提物与硝苯地平联用降压效果研究[J].茶叶科学,2015,(2):165-170,6.
