食品与发酵工业2015，Vol.41Issue(5)：157-159,3.DOI:10.13995/j.cnki.11-1802/ts.201505028
榛蘑多糖对大鼠血管内皮细胞的保护作用
Protective effects of polysaccharides from Armillaria mellea on vascular endothelium in rats
摘要
Abstract
To study the effect of polysaccharides from Armillaria mellea on endothelial cell injury in rats.Methods:Animal model was established by giving rats an injection of adrenaline and making it swim in ice-cold water.The number of circulating endothelial cells was measured with the immunofluorescence method,The levels of t-PA,AT-Ⅲ,6-keto-PGE1 α and TXB2 in plasma was measured by ELISA method.Results:Armillaria mellea polysaccharides decreased the number of circulating endothelial cells,increased the levels of t-PA and AT-Ⅲ,reduced TXB2 content as compared with the model group.However,there was no significant difference in the 6-keto-PGE1o level.Conclusion:Polysaccharides from Armillaria mellea present the protective effect on vascular endothelial cells.关键词
榛蘑多糖/血管内皮细胞/组织纤溶酶原激活物/抗凝酶Ⅲ/6-酮-前列腺素E1α/血栓素B2Key words
Armillaria mellea polysaccharide/vascular endothelium/t-PA/AT-Ⅲ/6-keto-PGE1α/TXB2引用本文复制引用
丛贺,周广亮,金梅花,沈明花..榛蘑多糖对大鼠血管内皮细胞的保护作用[J].食品与发酵工业,2015,41(5):157-159,3.基金项目
国家自然科学基金资助项目(No.30760150,No.81360088),吉林省科技发展计划项目(20140101223JC) （No.30760150,No.81360088）
