茶叶科学Issue(2)：125-130,6.
茯砖茶对小鼠肠道免疫功能调节作用的研究
Effects of Fuzhuan Brick Tea on the Adjustment of Intestinal Immune Function in Mice
摘要
Abstract
The aim of this study was to investigate the effects of FU brick tea water extracts on the adjustment of intestinal immune function of mice. Lavage with the Ampicillin to establish mice intestinal dysbacteriosis and immune dysfunction model. KM mice were random divided into six groups: normal control, natural recovery group, model group, three dose group of brick tea. The intestinal flora detection, the small intestinal mucous sIgA measurement, the measurement of IL-2 in serum, Serum albumin and total protein content detection and Ileum section pathological detection. The results showed that lavage with the Ampicillin 5 d, alteration of intestinal flora, the small intestinal mucous sIgA, the IL-2 in serum, serum albumin and total protein content were declined significantly compared with the normal saline group, in addition, the Ileum tissue slice showed obvious lesions. Compared with the natural recovery group, the small intestinal mucous sIgA, the IL-2 in serum, serum albumin and total protein content were increased significantly after the treatment with the brick tea water extracts. In the comparison between the treatment groups, the effect of high doses group were much better than the low doses group of treatment. It was concluded that the FU brick tea extracts can repair the damaged mucous membrane, showed the adjustment of the intestinal immune functions.关键词
茯砖茶/肠道免疫/sIgA/IL-2/肠道菌群Key words
Fuzhuan brick tea/immunity intestinal/sIgA/IL-2/intestinal flora分类
轻工纺织引用本文复制引用
吴香兰,刘仲华,曹丹,金莉莎,林勇..茯砖茶对小鼠肠道免疫功能调节作用的研究[J].茶叶科学,2013,(2):125-130,6.基金项目
湖南省重大科技专项“茯茶产业化关键技术研究与示范”（2008FJ1005）、国家自然科学基金项目 （）
