茶叶科学2016，Vol.36Issue(3)：245-249,5.
湖北青砖茶对 IBS-D 模型大鼠肠道敏感性的影响
The Effects of Hubei Qingzhuan Tea on Intestinal Sensitivity in IBS-D Mouse Model
李世刚 1郑倩倩 2何建刚 3肖长义 1柳蔚 1王慧 2刘锦程1
作者信息
- 1. 湖北长盛川青砖茶研究所，湖北 宜昌 443002
- 2. 三峡大学医学院，湖北 宜昌 443002
- 3. 三峡大学医学院，湖北 宜昌 443002
- 折叠
摘要
Abstract
The effects of Hubei Qingzhuan tea on intestinal sensitivity in IBS-D mouse model were investigated. The results showed, compared with the normal group, the control group had a significant reduction in the pain threshold, and marked increase in the serum level of inflammatory cytokines PGE2, TNF-alpha, tryptase. Compared with the control group, both the low and high dose of Qingzhuan tea significantly increased the pain threshold and markedly decreased the serum level of inflammatory cytokines PGE2, TNF-alpha, tryptase by a dose dependent manner. It is concluded that Qingzhuan tea could significantly decrease the intestinal sensitivity of IBS-D mice, which might be related to the inhibition of serum PGE2, TNF-alpha and tryptase levels.关键词
湖北青砖茶/IBS-D/肠道敏感性/结肠组织/炎症因子Key words
Hubei Qingzhuan tea/IBS-D/visceral sensitivity/colon tissue/inflammatory cytokines分类
农业科技引用本文复制引用
李世刚,郑倩倩,何建刚,肖长义,柳蔚,王慧,刘锦程..湖北青砖茶对 IBS-D 模型大鼠肠道敏感性的影响[J].茶叶科学,2016,36(3):245-249,5.
