食品科学2016，Vol.37Issue(13)：77-81,5.DOI:10.7506/spkx1002-6630-201613014
大果榕果实乙醇提取物抗氧化活性及对α-葡萄糖苷酶和乙酰胆碱酯酶抑制活性
Antioxidant Activity and Inhibitory Activity of Ethanol Extract from Ficus auriculata Fruits againstα-Glucosidase and Acetylcholine Esterase
摘要
Abstract
Total phenolics were extracted from Ficus auriculata fruits using 65%ethanol and quantified by the Folin phenol method. The antioxidant activity of the ethanol extract was assessed by DPPH, ABTS and hydroxyl radical scavenging assays and its inhibitory activity against alpha-glucosidase and acetylcholine esterase was also evaluated. Results showed that the fruit extract contained high levels of total phenolics (1.92 mg/g DW) and could scavenge DPPH, ABTS and hydroxyl radicals effectively in a concentration dependent manner with IC50 of 141.25, 91.20 and 45.71 µg/mL, respectively. It also exhibited strong inhibitory activity againstα-glucosidase in a concentration dependent manner with IC50 of 102.33 µg/mL. Similarly, it showed inhibitory activity against acetylcholine esterase with IC50 of 4.9 mg/mL. Therefore, the polyphenol-rich extract from Ficus auriculata fruits has strong antioxidant potential and inhibitory activity againstα-glucosidase and acetylcholine esterase.关键词
大果榕/果实多酚/抗氧化活性/自由基清除活性/α-葡萄糖苷酶抑制活性/乙酰胆碱酯酶抑制活性Key words
Ficus auriculata/fruit polyphenols/antioxidant activity/radical scavenging activity/α-glucosidase inhibitory activity/acetylcholine esterase inhibitory activity分类
农业科技引用本文复制引用
谭琳,郑晓燕,王甲水,马伏宁,康由发,臧小平,马蔚红..大果榕果实乙醇提取物抗氧化活性及对α-葡萄糖苷酶和乙酰胆碱酯酶抑制活性[J].食品科学,2016,37(13):77-81,5.基金项目
中国热带农业科学院海口实验站科研启动项目（HKZKY140204）；农业部财政项目 （）
