茶叶科学2016，Vol.36Issue(6)：557-566,10.
茶叶及其儿茶素类对乳腺癌的抑制作用
Inhibitory Effects of Tea and Tea Catechins on Breast Cancer
摘要
Abstract
Tea with high catechin contents has various health benefits. There are more than ten catechins in tea, among which epigallocatechin gallate (EGCG) is the most abundant. The inhibitory effects of tea and its major catechin (EGCG) on breast cancer were reviewed in the present paper, which included their abilities of suppressing carcinogen-induced ROS elevation and DNA damages, decreasing the responsiveness of cells to tumor necrosis factors, blocking the binding of estrogen to estrogen receptor, inhibiting DNA methylation, protecting mitochondria from oxidative damages and inhibiting tumor angiogenesis. The anti-proliferation and anti-metastasis of cancer cells and their synergistic effects with anticancer drugs were also mentioned. The inconsistent results in previous studies and directions for future research were finally discussed.关键词
茶/儿茶素/抗癌/抗氧化剂/雌激素受体/抗增殖/转移Key words
tea/catechins/anticancer/antioxidant/estrogen receptor/anti-proliferation/metastasis分类
轻工纺织引用本文复制引用
乔如颖,李明,郑新强,陆建良,叶俭慧,王开荣,梁月荣..茶叶及其儿茶素类对乳腺癌的抑制作用[J].茶叶科学,2016,36(6):557-566,10.基金项目
2014年度宁波市农业攻关项目 （）
