肉类研究2016，Vol.30Issue(11)：1-5,5.DOI:10.15922/j.cnki.rlyj.2016.11.001
牛肝中牛磺酸对免疫抑制小鼠免疫及抗氧化能力的影响
Effect of Taurine from Bovine Liver on Immune Functions and Antioxidant Capacity in Immunosuppressed Mice
梁肖娜 1叶馨阳 1孔彦文 1张祎炜 1杨梅 1曹雪妍 1武俊瑞 1岳喜庆1
作者信息
- 1. 沈阳农业大学食品学院，辽宁沈阳 110866
- 折叠
摘要
Abstract
Taurine is one of the conditionally essential amino acids in the human body and it plays an important role in the physiological functions of the human body. In this research, our purpose was to evaluate the effect of taurine on immune functions and antioxidant capacity in animals. A mouse model of immunosuppression was established by intraperitoneal injection of mice of different ages with cyclophosphamide, and then the immunosuppressed mice were intraperitoneally injected with various doses of natural taurine physically extracted from bovine liver. After 12 hours, we measured immunological indicators and antioxidant parameters and correlated immunological indicators with total antioxidant capacity (T-AOC). The results showed that taurine at both high and low doses had an immunoregulatory effect and improved antioxidant capacity in immunosuppressed mice of different ages and immune functions and antioxidant capacity in juvenile and old mice administered with taurine reached or exceeded the normal level. Correlation analysis revealed that there was a positive correlation between immune functions and antioxidant capacity in mice.关键词
牛磺酸/环磷酰胺/免疫抑制/小鼠/抗氧化Key words
taurine/cyclophosphamide/immunosuppression/mice/antioxidant分类
轻工纺织引用本文复制引用
梁肖娜,叶馨阳,孔彦文,张祎炜,杨梅,曹雪妍,武俊瑞,岳喜庆..牛肝中牛磺酸对免疫抑制小鼠免疫及抗氧化能力的影响[J].肉类研究,2016,30(11):1-5,5.
