食品与机械2016,Vol.32Issue(12):148-151,4.DOI:10.13652/j.issn.1003-5788.2016.12.032
谷朊粉水解物对MT X诱导大鼠小肠炎症的修复作用
Effect of wheat gluten hydrolysate on the recovery of intestinal mucositis in methotrexate treated rats
摘要
Abstract
To investigate the effect of wheat gluten hydrolysate (WGH)rich in glutamine prepared through the enzymatic hydrolysis by trysin on small intestinal mucosal by methotrexate induced mu-cositis model in rats.The results showed that the WGH can signifi-cantly increase intestinal mucosa weight,villus height,crypt depth, protein and DNA content,decrease diamine oxidase level in plasma and increase glutathione content of small intestine mucosa.The WGH can efficiently alleviate the intestinal mucosal injury in rats.关键词
谷氨酰胺/谷朊粉水解物/氨甲蝶呤/小肠炎/大鼠Key words
Glutamine/wheat gluten hydrolysate/methotrexate/in-testinal mucositis/rats引用本文复制引用
严斌,刘丽娅,王延州,周闲容,周素梅..谷朊粉水解物对MT X诱导大鼠小肠炎症的修复作用[J].食品与机械,2016,32(12):148-151,4.基金项目
农业部“引进国际先进农业科学技术”项目(编号:2016-X31) (编号:2016-X31)
农业部公益性行业(农业)科研专项(编号:201303071) (农业)
国家自然科学基金项目(编号:31571768) (编号:31571768)