食品科学2017，Vol.38Issue(6)：315-320,6.DOI:10.7506/spkx1002-6630-201706049
超高效液相色谱-串联质谱法测定猪肉中β-受体激动剂残留量的不确定度分析
Uncertainty Evaluation for the Determination of β-Agonists in Pork by Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry
宁霄 1金绍明 1梁瑞强 1曹进 1张庆生1
作者信息
- 1. 中国食品药品检定研究院,北京 100050
- 折叠
摘要
Abstract
This study aimed to evaluate the uncertainty of measurement in the determination of salbutamol,clenbuterol hydrochloride and ractompaine in pork by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).According to JJF 1135-2005 Evaluation of Uncertainty in Chemical Analysis Measurement and JJF 1059.1-2012 Evaluation and Expression of Uncertainty in Measurement,a mathematical model was established for uncertainty evaluation.The sources of uncertainty that may be introduced were analyzed and each component of uncertainty was quantified for the calculation of the combined uncertainty.The results showed that an expanded uncertainty of 0.25 μtg/kg (k =2) was obtained for the determination of the presence of 1.99 μg/kg salbutamol in pork,the expanded uncertainty was 0.24 μg/kg (k =2) for the determination of pork samples containing 2.04 and 1.97 μg/kg salbutamol.The preparation of standard solution,curve fitting and measurement repeatability were found to be the main sources of uncertainty.关键词
超高效液相色谱-串联质谱/沙丁胺醇/盐酸克伦特罗/莱克多巴胺/不确定度/猪肉Key words
ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS)/salbutamol/clenbuterol hydrochloride/ractompaine/uncertainty/pork分类
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宁霄,金绍明,梁瑞强,曹进,张庆生..超高效液相色谱-串联质谱法测定猪肉中β-受体激动剂残留量的不确定度分析[J].食品科学,2017,38(6):315-320,6.
