食品与机械2017，Vol.33Issue(2)：126-129,4.DOI:10.13652/j.issn.1003-5788.2017.02.027
葛根复合固体饮料保护化学性肝损伤的研究
Study on protective effect of puerarin solid beverage on chemical hepatic injury
黄敏 1郑建仙 1董庆亮 1李加兴2
作者信息
- 1. 华南理工大学,广东广州 510640
- 2. 吉首大学,湖南吉首416000
- 折叠
摘要
Abstract
With puerarin solid beverage made of pueraria,hawthorn,acid gill,okra,Rhizoma zingiberis,corn peptide and crystalline fructose as the test substance,to study its protection function on chemical hepatic injury by CCl4 in the Wistar mice.Wistar mice were randomly allocated to negative control group,model control group and three experiment groups,which were treated with intubation of distilled water or 1.08,2.17 or 4.33 g/kg test substance per day for 30 days.Groups which except negative control group were treated with gastric intubation of CCl4,and the chemical hepatic injury model was gained.The level of serum alanine aminotransferase (ALT),aspartate aminotransferase (AST),triglyceride (TG) were detected,and then take the liver weight and pathological section for the liver coefficients and observing the pathological changes of liver.Compared with model control group,ALT,AST and liver coefficients were decreased significantly in experiment groups after gastric intubation of CCl4,also with the mitigatory pathologic changes.And the highest dose experiment group (experiment Ⅲ) gained the most significant effects.Thus,the test substance could protect liver against chemical hepatic injury.关键词
葛根/玉米肽/化学性肝损伤/动物试验Key words
Radix puerariae/corn peptides/chemical hepatic injury/animal experiment引用本文复制引用
黄敏,郑建仙,董庆亮,李加兴..葛根复合固体饮料保护化学性肝损伤的研究[J].食品与机械,2017,33(2):126-129,4.
