现代食品科技2017，Vol.33Issue(3)：35-39,73,6.DOI:10.13982/j.mfst.1673-9078.2017.3.006
多穗柯挥发性组分分析及抗癌活性的初步研究
Analysis of the Volatile Components of Lithocarpus polystachyus Rehd.and a Preliminary Study of Their Anticancer Activity
摘要
Abstract
Lithocarpus polystachyus Rehd.was selected as a starting material to extract volatile components using simultaneous distillation extraction (SDE) method.The composition of volatile components was analyzed by gas chromatography-mass spectrometry (GC-MS).Subsequently,the anticancer activities of the volatile components and major monomeric substances of Lithocarpus polystachyus Rehd.were studied using mouse hepatoma cells (Hepa1c1c7).A cell viability of greater than 50％ and quinone reductase (QR) induction activity greater than or equal to 2 were set as the activity indicators.The results showed that a total of over 80 types of major volatile compounds were identified by the GC-MS analysis,accounting for 92.56％ of the total volatiles.Ketones,alcohols,and aldehydes were the major chemical types.Among them,geranylacetone,β-ionone,nonanal,and spathulenol were the most abundant volatile components.The measurement of anti-cancer activity indicated that the induced QR activity was amplified when the concentration of volatile components ofLithocarpus polystachyus Rehd.was (27.50±0.10) μg/mL.And the concentrations of linalool,geranylacetone,and nonanal,the three main volatile components that enhanced the induced QR activity,were (54.53±0.10) μg/mL,(283.10±0.10) pg/mL,and (297.77±0.12) μg/mL,respectively.关键词
多穗柯/挥发性组分/成分分析/抗癌活性Key words
Lithocarpus polystachyus Rehd/volatile components/composition analysis/anti-cancer activity引用本文复制引用
燕妮,王佐,高雄,张媛媛,林晓蓉,李斌,陈忠正..多穗柯挥发性组分分析及抗癌活性的初步研究[J].现代食品科技,2017,33(3):35-39,73,6.基金项目
现代农业产业技术体系建设专项资金(CARS-23) （CARS-23）
