现代食品科技2017，Vol.33Issue(5)：39-46,76,9.DOI:10.13982/j.mfst.1673-9078.2017.5.007
雪莲果多糖降血脂及降血糖活性的研究
Hypoglycemic and Hypolipidemic Activities of Smallanthus sonchifolius (Yacon) Polysaccharides
摘要
Abstract
An animal model of preventive hyperlipidemia was used to investigate the hypolipidemic activity of polysaccharides extracted from yacon.Body weight and the levels of serum total cholesterol (TC),triglyceride (TG),low-density lipoprotein cholesterol (LDL-C),and high-density lipoprotein cholesterol (HDL-C) were measured in mice with or without yacon polysaccharide treatment.The results showed that polysaccharides from yacon had no obvious effect on mouse body weight.The crude polysaccharides and pure polysaccharides remarkably decreased the serum TC,TG,and LDL-C levels in hyperlipidemic mice (p＜0.01).Purc polysaccharides clearly increased the serum HDL-C levels (p＜0.05) and the hepatic TG and TC levels (p＜0.01) in mice.The results showed that the polysaccharides from yacon clearly inhibited the blood lipid level elevations caused by a high fat diet,and the pure polysaccharides had better effect than the crude polysaccharides.Additionally,the hypoglycemic activity of yacon polysaccharides was investigated using a mouse model of hyperglycemia.The result showed that the lowand medium-dose groups of crude polysaccharides from yacon decreased fasting blood glucose levels significantly (p＜0.05),demonstrating that the polysaccharides from yacon have a hypoglycemic effect in vivo.关键词
雪莲果多糖/降血脂/降血糖Key words
Yacon polysaccharide/hypolipidemia/hypoglycemia引用本文复制引用
朱振元,李楠,张静怡,连红玉..雪莲果多糖降血脂及降血糖活性的研究[J].现代食品科技,2017,33(5):39-46,76,9.基金项目
国家星火计划重点项目(2015GA610001) （2015GA610001）
天津市农业科技成果转化与推广项目(201502180) （201502180）
