食品科学2017，Vol.38Issue(11)：269-275,7.DOI:10.7506/spkx1002-6630-201711043
CRISPR-Cas系统在食品微生物中的应用研究进展
Progress in CRISPR-Cas System Application in Food Microbiology
摘要
Abstract
The clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 nuclease (Cas9) system has been widely applied in genome editing in microbiology due to its high efficacy,versatility and easy programmability.Herein,we review its applications in the field of food microbiology,especially in food fermentation and pathogenic microbiology.Also,the major factors affecting the genome editing efficacy and future perspectives for the development of this system are discussed.Finally,this review is expected to provide references for research in food microbiology by using CRISPR-Cas9 system.关键词
CRISPR-Cas系统/食品微生物/基因编辑Key words
CRISPR-Cas system/food microbiology/genome editing分类
轻工纺织引用本文复制引用
张玉洁,宋育阳,秦义,刘延琳..CRISPR-Cas系统在食品微生物中的应用研究进展[J].食品科学,2017,38(11):269-275,7.基金项目
国家自然科学基金面上项目(31571812) （31571812）
国家自然科学基金青年科学基金项目(31301541) （31301541）
国家现代农业(葡萄)产业技术体系建设专项(CARS-30-jg-3) （葡萄）
中央高校基本科研业务费专项资金项目(QN2013021) （QN2013021）
