轻工学报2017，Vol.32Issue(4)：43-48,6.DOI:10.3969/j.issn.2096-1553.2017.4.007
相转移催化法合成α-紫罗兰醇-β-D-葡萄糖苷工艺研究
Study on synthesis of α-ionol-β-D-glucoside by phrase transfer catalytic method
摘要
Abstract
α-ionol was synthesized from α-ionone via the selective reduction.α-ionol-β-D-glucoside was synthesized from α-ionol via the reaction with tetra-O-α-acetyl-D-glucopyranosyl bromide under the phase transfer catalyst to give the corresponding α-ionol-2,3,4,6-tetra-O-acetyl-β-D-glucoside,followed by deacetylation.The appropriate conditions for this glucosidation reaction were as follows:10% tetrabutyl ammonium bromide was added to catalyze a reaction between Br-glucose-tetraacetateand α-ionol at a ratio of 1.6：1 in CHCl3-H2O allowed to proceed for 8 h at 60 ℃.The yield rate of glycosylation reaction was 30%.The target products were characterized β-configuration by FT-IR,1H NMR and ESI-MS.关键词
相转移催化法/α-紫罗兰醇-β-D-葡萄糖苷/糖苷化Key words
phrase transfer catalytic method/α-ionol-β-D-glucoside/glycosylation分类
化学化工引用本文复制引用
张改红,刘宇,李雪龙,潘鹏,柯宁,白冰,毛多斌..相转移催化法合成α-紫罗兰醇-β-D-葡萄糖苷工艺研究[J].轻工学报,2017,32(4):43-48,6.基金项目
国家级大学生创新创业训练计划项目(201510462046) （201510462046）
河南省教育厅科学技术重点研究项目(14A550017) （14A550017）
