齐墩果酸滴丸的质量标准研究OA北大核心CSTPCD
Study on Quality Standard of Oleanolic Acid Dripping Pills
目的:建立齐墩果酸滴丸的质量标准.方法:鉴别制剂性状,检测制剂重量差异、溶散时限;采用超高效液相色谱法测定制剂中齐墩果酸的含量:色谱柱为ACQUITY UPLC BEH C18,流动相为乙腈-水(70:30,V/V),流速为0.30 mL/min,检测波长为206 nm,柱温为30℃,进样量为5μL.结果:制剂鉴别特征明显,丸重差异为37.62%~46.56%,溶散时间均为24 min.齐墩果酸检测质量浓度线性范围为0.006~0.06 mg/m…查看全部>>
OBJECTIVE:To establish the quality standard of Oleanolic acid dripping pills. METHODS:The property of the preparation was identified,and weight difference and dissolution time limit were detected. UPLC method was adopted to determine the content of oleanolic acid in the preparation. The determination was performed on ACQUITY UPLC BEH C18 column with mo-bile phase consisted of acetonitrile-water (70:30,V/V) at the flow rate of 0.30 mL/min. The detection…查看全部>>
李祥;梁颖;杨新建
天津市中医药研究院附属医院,天津 300120天津市中医药研究院附属医院,天津 300120天津市中医药研究院附属医院,天津 300120
医药卫生
齐墩果酸滴丸超高效液相色谱法齐墩果酸质量标准
Oleanolic acid dripping pillsUPLCOleanolic acidQuality standard
《中国药房》 2017 (21)
2994-2996,3
评论