现代食品科技2017，Vol.33Issue(7)：9-16,8.DOI:10.13982/j.mfst.1673-9078.2017.7.002
短期摄食卵黄磷脂与鱼油对高脂小鼠脂质代谢的影响
Effects of Short-term Consumption of Fish Oil-egg-phospholipid on Lipid Metabolism in Mice Fed a High-fat Diet
摘要
Abstract
The effects of short-term consumption of docosahexaenoic acid (DHA)-enriched phospholipids,DHA-enriched triglycerides,and the combination of DHA-enriched triglycerides and egg-phospholipids on lipid metabolism in mice fed a high-fat diet were compared.C57BL/6J mice were divided into five groups:low-fat group,high-fat group,DHA-enriched phospholipid group,DHA-enriched triglyceride group,and DHA-enriched triglyceride-egg-phospholipids combination group.Mice were fed the high-fat diet for a week;thereafter,lipid levels in the serum,liver,and brain were measured,along with the fatty acid compositions in the liver and brain.The short-term dietary supplementation of DHA could improve lipid metabolism in mice to different degrees.The serum triglyceride (TG) concentration was significantly reduced by DHA-enriched phospholipids and by the combination of DHA-enriched triglycerides and egg-phospholipids to the same degree.DHA-enriched phospholipids were superior to the combination of DHA-enriched triglycerides and egg-phospholipids in decreasing total serum cholesterol.The hepatic TG level in the combination group was notably lower than that in the high-fat group.However,no significant difference was observed in the hepatic TG level between the DHA-enriched phospholipids group and the combination group.Furthermore,DHA-enriched phospholipids and the combination of DHA-enriched triglycerides and egg-phospholipids could significantly increase the content of DHA in the liver and brain.DHA-enriched phospholipids could more effectively improve lipid metabolism in the serum and liver of mice fed a high-fat diet,and showed the highest increase in brain DHA level.关键词
脂质代谢/二十二碳六烯酸/甘油三酯/磷脂/脂肪酸组成Key words
lipid metabolism/docosahexaenoic acid (DHA)/triglyceride/phospholipid/fatty acid composition引用本文复制引用
史豪豪,车红霞,高翔,崔洁,王玉明,薛长湖..短期摄食卵黄磷脂与鱼油对高脂小鼠脂质代谢的影响[J].现代食品科技,2017,33(7):9-16,8.基金项目
国家自然科学基金资助项目(31371757) （31371757）
